Transfer RNA genes in pieces
نویسندگان
چکیده
منابع مشابه
Transfer RNA genes in pieces.
The short genes encoding transfer RNA (tRNA) molecules are highly conserved in both sequence and structure, reflecting the central role of tRNA in protein biosynthesis. The frequent occurrence of fragmented intron-containing tRNAs that require processing to form contiguous molecules is therefore surprising. Recent discoveries of permuted and split tRNA genes have added to the apparent creativit...
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randau & Söll (2008) suggest that the anticodon loop region of transfer rNa (trNa) genes is the target site of a huge variety of mobile genetic elements and that this resulted in the evolution of trNa genes in pieces. they therefore suggest that the presence of introns in the anticodon loop might not be a plesiomorphic trait that is important in trNa origin (Di giulio, 2006), but an acquired tr...
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All eukaryotic (and many bacterial) RNAs descend from larger precursors, some of them thousands of times larger than the final product and others just a few nucleotides longer. The genomes of eukaryotes are pastiches of both assembled modules and subsequently introduced mobile elements, and the resulting baroque design has led to a situation in which almost all transcripts require trimming. The...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2008
ISSN: 1469-221X,1469-3178
DOI: 10.1038/embor.2008.101